Search ETDs:
Neural Mechanisms Underlying Stress-Induced Depression and Its Prevention

2011, BS, Kent State University, College of Arts and Sciences / Department of Biological Sciences.
Psychological and physical stressors stimulate the noradrenergic system which results in the induction of cytokine production via norepinephrine acting on β-adrenergic receptors. These cytokines, especially IL-1β, and the dysregulation of the noradrenergic system are implicated in depressive behavior. Current antidepressants increase norepinephrine in the brain which often leads to worsening of depressive symptoms during early stages of treatment. Blocking the effects of norepinephrine, with a β-adrenergic receptor blocker like Propranolol, may prevent stress-induced depression.
John Johnson (Advisor)
Douglas Kline (Committee Member)
Bansidhar Datta (Committee Member)
Manfred van Dulmen (Committee Member)

Recommended Citations

Hide/Show APA Citation

Nagabhushan, S. (2011). Neural Mechanisms Underlying Stress-Induced Depression and Its Prevention. (Electronic Thesis or Dissertation). Retrieved from https://etd.ohiolink.edu/

Hide/Show MLA Citation

Nagabhushan, Sahana. "Neural Mechanisms Underlying Stress-Induced Depression and Its Prevention." Electronic Thesis or Dissertation. Kent State University, 2011. OhioLINK Electronic Theses and Dissertations Center. 25 May 2015.

Hide/Show Chicago Citation

Nagabhushan, Sahana "Neural Mechanisms Underlying Stress-Induced Depression and Its Prevention." Electronic Thesis or Dissertation. Kent State University, 2011. https://etd.ohiolink.edu/

Files

ksuhonors1304462392.pdf (661.82 KB) View|Download