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  • 1. Oh, Joonyoung Numerical study of micro-scale damage evolution in time dependent fracture mechanics

    Doctor of Philosophy, The Ohio State University, 2005, Mechanical Engineering

    In part 1, intergranular cavity growth in regimes, where both surface diffusion and deformation enhanced grain boundary diffusion are important, is studied. In order to continuously simulate the cavity shape evolution and cavity growth rate, a fully-coupled numerical method is proposed. Based on the fully-coupled numerical method, a gradual cavity shape change is predicted and this leads to the adverse effect on the cavity growth rate. As the portion of the cavity volume growth due to jacking and viscoplastic deformation in the total cavity volume growth increases, spherical cavity evolves to V-shaped cavity. The obtained numerical results are physically more realistic compared to results in the previous works. The present numerical results suggest that the cavity shape evolution and cavity growth rate based on the assumed cavity shape, spherical or crack-like, simply cannot be used in this regime. In part 2, intergranular creep failure of high temperature service material under a stress-controlled unbalanced cyclic loading condition is studied. The experimentally verified Murakami-Ohno strain hardening creep law and Norton's creep law are incorporated into the Tvegaard's axis-symmetric model for the constrained grain boundary rupture analysis. Based on the physically realistic Murakami-Ohno creep law, it is shown that the cavity growth becomes unconstrained upon the stress reversal from compression to tension. This leads to the prediction that the material life under a cyclic loading condition is shorter than that under a constant loading. Based on the classical Norton's law, the predicted material life under a cyclic loading condition remains the same as that under a constant loading. The obtained numerical results qualitatively match with recent experimental results by Arai, where the life under a cyclic loading can be much shorter than that under a constant loading. There are many cases where engineers use a simple Norton's creep law because of its simplicity. T (open full item for complete abstract)

    Committee: Noriko Katsube (Advisor) Subjects:
  • 2. Yip, Ka Wa Optical pumping of multiple atoms in the single photon subspace of two-mode cavity QED

    Master of Science, Miami University, 2015, Physics

    We consider N four level atoms coupled to an orthogonally polarized, degenerate two-mode optical cavity. Starting with the atoms prepared in one of the degenerate ground states a single photon introduced into the driven cavity mode will be recycled to pump multiple atoms to the other ground state. For two atoms we analytically calculate the steady state using quantum trajectory equations and show that the system makes stochastic transitions between two different subspaces with the transition correlated with the emission of a polarized photon from one of the two modes of the cavity. In this way the long time evolution of the atomic state can be monitored by direct photodetection of the cavity decay passed through a polarizing beam splitter. We also investigate the dynamics of the approach to the steady state by numerical simulations carried out using the Quantum Toolbox in Python (QuTiP).

    Committee: James Clemens Dr. (Advisor); Perry Rice Dr. (Committee Member); Samir Bali Dr. (Committee Member) Subjects: Physics
  • 3. Wu, Vincent Design and Testing of a High Gradient Radio Frequency Cavity for the Muon Collider

    PhD, University of Cincinnati, 2002, Arts and Sciences : Physics

    This thesis describes the design and testing of a high gradient RF cavity for the muon cooling channel of the muon collider. The 805 MHz multi-cell open iris cavity was high power tested with a 12 MW klystron in a superconducting solenoid environment. The cavity reached 21 MV/m for peak klystron power in the absence of the solenoidal field. During magnetic field operation, the cavity suffered serious surface damage and RF breakdown. Dark current in excess of 400 mA was observed. Present R&D results imply that the cavity is not suitable for the muon collider.

    Committee: Dr. Randy Johnson (Advisor) Subjects:
  • 4. Heinrichs, Joseph Plasma Assisted Combustion and Flameholding in High Speed Cavity Flows

    Master of Science, The Ohio State University, 2012, Mechanical Engineering

    This thesis presents an experimental study of non-equilibrium, low temperature, large volume plasma assisted ignition and flameholding in high-speed, non-premixed fuel-air flows. The plasma is produced between two electrodes powered by a high-voltage, nanosecond pulse generator operated at a high pulse repetition rate. Ignition in this type of plasma occurs due to production of highly reactive radicals by electron impact excitation and dissociation, as opposed to more common thermal ignition. Previously, it has been shown that this type of plasma can reduce ignition delay time and ignition temperature. The experiments performed in this thesis focus on application of these plasmas to ignition, and flameholding in high-speed cavity flows. The experiments discussed in this thesis continue previous work using a high-speed combustion test section with a larger cavity, and the previous results are compared to the present work. Several modifications have been made to the test section and electrodes compared to the design used in previous work in order to reduce the cavity effect on the main flow and maintain diffuse plasma between the electrodes in the cavity. The electrodes used in these experiments are placed in a cavity recess, used to create a recirculation flow region with long residence time, where ignition and flameholding can occur. In order to analyze the nanosecond pulse plasma and the flame, various diagnostics were used, including current and voltage measurements, UV emission measurements, ICCD camera imaging, static pressure measurements, and time-averaged emission spectroscopy. The experiments in this thesis were performed at relatively low pressures (P=150-200 torr) using hydrogen and ethylene fuels injected into the cavity. Current and voltage measurements showed that ~1-2 mJ was coupled to the plasma by each pulse. ICCD imaging and UV emission data revealed that the plasma sustained in quiescent air was diffuse. When ethylene was injected into the cavity (open full item for complete abstract)

    Committee: Igor Adamovich PhD (Advisor); Walter Lempert PhD (Committee Member) Subjects: Mechanical Engineering
  • 5. Napper, Kristin EFFECTS OF MULTIPLE FACTORS ON NEST-SITE SELECTION AND NESTING SUCCESS OF EASTERN BLUEBIRDS (Sialia sialis)

    Master of Science, University of Akron, 2005, Biology

    Eastern Bluebirds (Sialia sialis) are secondary cavity-nesting species that are overcoming declines in their populations caused by habitat fragmentation and interspecific interactions with other native cavity nesting species, such as Tree Swallows (Tachycineta bicolor) and House Wrens (Troglodytes aedon), and invasive cavity-nesting species, such as the House Sparrow (Passer domesticus). House Sparrows and House Wrens will compete fiercely with the bluebirds for nest-boxes and often harm the adults and/or young in the process. Tree Swallows will usually live harmoniously with bluebirds as long as there are enough available nest-sites to choose from. During the breeding seasons (March through August) of 2003 and 2004, the effects of multiple factors, such as competitors (both native and invasive) and various nest-box characteristics, on nest-site selection and nesting success of Eastern Bluebirds were observed. A total of 191 nest-boxes erected within the boundaries of the Bath Nature Preserve, Bath, OH, and the Metro Parks serving Summit County were used. Selection of a nest-box by all competitors was determined by the nesting activity observed within the box. A bluebird nest with at least one nestling fledged was considered successful. Results and conclusions from this study were used to develop curricula for local Akron City Schools, and will lead to a more concrete understanding of which competitors and/or which nest-box characteristics influence the nest-site selection and nesting success of Eastern Bluebirds.

    Committee: Randall Mitchell (Advisor) Subjects:
  • 6. Song, Zhuoqing (Maxwell) Particle Shadow Velocimetry and its Potential Applications and Advantages vis-a-vis Particle Image Velocimetry

    Master of Sciences (Engineering), Case Western Reserve University, 2025, EMC - Mechanical Engineering

    Particle Image Velocimetry (PIV) is a technique that allows velocity measurements of a 2D plane of a fluid flow by illuminating seeding particles in the fluid with a laser sheet. However, the use of laser is often costly, introduces complexity, and poses a challenge in near-wall measurements due to light scattering from surfaces. Particle shadow velocimetry (PSV) is a novel velocimetry technique with the potential of being a low-cost, laser-free alternative to the established PIV technique. It works by tracking shadows cast by the seeding particles on an illuminated background. Little is known about the accuracy of this technique validated against PIV. This study starts by characterization the performance of this technique, presents results from two experiments using both PIV and PSV on the same plane, and discusses its advantages and potential applications.

    Committee: Bryan Schmidt (Committee Chair); Chengyu Li (Committee Member); Chirag Kharangate (Committee Member) Subjects: Aerospace Engineering; Experiments; Fluid Dynamics; Mechanical Engineering
  • 7. Pafford, Jeffrey In vivo evaluation of intraoperative and postoperative pain of hand/rotary/ultrasound technique in the root canals of vital and necrotic teeth /

    Master of Science, The Ohio State University, 2007, Graduate School

    Committee: Not Provided (Other) Subjects:
  • 8. Schultz, Ryan Modeling and identification of an acoustic actuator for cavity flow control /

    Master of Science, The Ohio State University, 2006, Graduate School

    Committee: Not Provided (Other) Subjects:
  • 9. Just, Gabriel Cavity ringdown spectroscopy of the A-X electronic transition of the phenyl peroxy radical /

    Master of Science, The Ohio State University, 2005, Graduate School

    Committee: Not Provided (Other) Subjects:
  • 10. Nayak, Indranil Data-Driven Koopman Reduced-Order Models for Kinetic Plasmas and Electromagnetic Cavities

    Doctor of Philosophy, The Ohio State University, 2024, Electrical and Computer Engineering

    We present an exposition on Koopman operator-based reduced-order modeling of high-dimensional electromagnetic (EM) systems exhibiting both linear and nonlinear dynamics. Since the emergence of the digital age, numerical methods have been pivotal in understanding physical phenomena through computer simulations. Computational electromagnetics (CEM) and computational plasma physics (CPP) are related yet distinct branches, each addressing complex linear and nonlinear electromagnetic phenomena. CEM primarily focuses on solving Maxwell's equations for intricate structures such as antennas, cavities, high-frequency circuits, waveguides, and scattering problems. In contrast, CPP aims to capturing the complex behavior of charged particles under electromagnetic fields. This work specifically focuses on the numerical simulation of electromagnetic cavities and particle-in-cell (PIC) kinetic plasma simulations. Studying electromagnetic field coupling inside metallic cavities is crucial for various applications, including electromagnetic interference (EMI), electromagnetic compatibility (EMC), shielded enclosures, cavity filters, and antennas. However, time-domain simulations can be computationally intensive and time-consuming, especially as the scale and complexity of the problem increase. Similarly, PIC simulations, which are extensively used for simulating kinetic plasmas in the design of high-power microwave devices, vacuum electronic devices, and in astrophysical studies, can be computationally demanding, especially when simulating thousands to millions of charged particles. Moreover, the nonlinear nature of the complex wave-particle interactions complicates the modeling task. Data-driven reduced-order models (ROMs), which have recently gained prominence due to advances in machine learning techniques and hardware capabilities, offer a practical approach for constructing "light" models from high-fidelity data. The Koopman operator-based data-driven ROM is a powerful met (open full item for complete abstract)

    Committee: Mrinal Kumar (Advisor); Fernando Teixeira (Advisor); Ben McCorkle (Committee Member); Balasubramaniam Shanker (Committee Member) Subjects: Electrical Engineering; Electromagnetics; Engineering; Physics; Plasma Physics
  • 11. Doshi, Parshwanath Modal Description and Passive Control of a Shear Layer within a Supersonic Multistream Jet

    Doctor of Philosophy, The Ohio State University, 2023, Mechanical Engineering

    Since its inception in the 1930s, the evolution of the jet engine has largely been dictated by the need to improve propulsion and fuel economy while reducing noise and environmental impact. Although rapid engineering advancements have enabled progress towards these design objectives, they have also yielded increasingly complex air flowpaths, and further improvements have been inhibited by a lack of understanding of the fluid dynamics. This is because the flowfields are typically characterized by interacting turbulent jets, shear layers, boundary layers, and wakes which evolve in the presence of supersonic expansion and shock waves. Additionally, they are rife with fluid dynamic instabilities that may pose a challenge to the structural, thermal and acoustic performance of the engine. To address this knowledge gap, the present work builds upon a collaborative numerical and experimental campaign between The Ohio State University and Syracuse University, that investigates a supersonic, multistream, airframe-integrated, rectangular nozzle architecture that is representative of emerging industry designs. The configuration consists of a contoured, single-sided expansion nozzle on one side, and a flat aft-deck surface representing the airframe on the other. Within the nozzle, two rectangular streams - a supersonic (Mach 1.6) "core" stream and sonic (Mach 1) "deck" stream - interact after being initially separated by a thick splitter plate. The flow conditions and geometry of the nozzle render a complex 3D flowfield which has been extensively examined in previous work. It is also comprised of a shear layer instability which is initiated at the splitter plate trailing edge (SPTE) and is associated with large vortical structures and a strong tone that have a deleterious effect on the acoustic and structural characteristics of the nozzle. Although previous research works attempting to mitigate the instability by thinning out the SPTE have been promising, such (open full item for complete abstract)

    Committee: Datta Gaitonde (Advisor); Jen-Ping Chen (Committee Member); Seung Hyun Kim (Committee Member) Subjects: Aerospace Engineering; Mechanical Engineering
  • 12. Shen, Jianhao Compact Energy Efficient 1-D Photonic Crystal Cavity Electro-Optical Switch

    Master of Science (M.S.), University of Dayton, 2022, Electro-Optics

    Over the past decade, the benefits of photonics over electronics such as ability to achieve high bandwidth, high interconnectivity and low latency, together with the high maturity of silicon photonics foundries has spurred robust applications in optical transceivers and in classical and quantum computing. In both application areas, silicon microring resonators (MRRs) using carrier depletion effects in p-n junctions represent the most compact optical switches manufacturable at high volume with 5.2fJ/bit power consumption. Matrix computation approaches as well wavelength-division-multiplexed modulators require several MRRs in series coupled to the silicon waveguide optical bus. Such architectures are potentially limited to ∼ 30 by the limited free-spectral range (FSR) of an individual MRR. However, with ever increasing data volumes, there is a need to process larger matrices and/or modulate more wavelengths in the telecom bands along a single silicon bus channel. Photonic crystal (PC) dielectric structures confine an optical mode to sub-micron mode volumes and have shown the potential to reach 0.1fJ switching energies. Research till date on PC devices have centered on either inline one-dimensional PC nanobeam structures or on two-dimensional PC waveguide coupled microcavity configurations. In this paper, through detailed electrical and optical simulations, we demonstrate the feasibility to achieve compact switches with 1dB insertion loss, 5dB extinction and ∼ 260aJ/bit energies in oxide-embedded bus-coupled 1D photonic crystal nanobeam platform. Resonance linewidths <0.1nm and FSR >100nm enable energy efficient computing of larger matrices with ∼200 resonators in series separated by ∼ 0.5nm wavelength over the entire C+L bands. Device architectures will be presented.

    Committee: Swapnajit Chakravarty (Advisor); Partha Banerjee (Committee Member); Andrew Sarangan (Committee Member); Swapnajit Chakravarty (Committee Chair) Subjects: Engineering; Optics
  • 13. Farnkopf, Ian The olfactory anatomy and upper respiratory tracts of whales, dolphins, and their terrestrial relatives: Perspectives from morphology, histology, embryology, and evolutionary biology

    PHD, Kent State University, 2022, College of Arts and Sciences / School of Biomedical Sciences

    Having transitioned from a terrestrial lifestyle to an aquatic one over roughly 50 million years, cetaceans (whales, dolphins, and porpoises) make for prime subjects of study of respiratory and olfactory anatomy. As obligately aquatic mammals, they are often considered to have reduced olfactory anatomy. Here, I provide evidence that baleen whales have retained this anatomy, and toothed whales lack olfactory anatomy. In reconstructing the upper respiratory tracts of prenatal dolphins from computed tomography, I document the anatomy of the air sacs, pterygoid sinus systems, and asymmetries thereof. Olfactory anatomy was absent. However, in bowhead whales (Balaena mysticetus), a species of baleen whale, nasal chambers and turbinates were visible in prenatal development. I describe and clarify the anatomy within their nasal chambers. Olfactory epithelium, identified histologically, covers the dorsalmost and caudalmost corner of the nasal chamber, including some of the ethmoturbinates. I identify olfactory epithelium using explicit criteria of mammalian olfactory epithelium. Immunohistochemistry revealed the presence of olfactory marker protein, which is only found in mature olfactory sensory neurons. Although it seems that these neurons are scarce in bowhead compared to typical terrestrial mammals, our results suggest that bowheads have a functional sense of smell, which they may use to find prey. The closest living relatives of cetaceans are artiodactyls, even-toed ungulates, such as sheep, camels, and giraffes. I used Cetartiodactyla, the clade that comprises artiodactyls and cetaceans, as the taxon to test the relationships found in Bird et al. (2018). They found that once body mass and phylogeny are accounted for, it is possible to use the surface area of the cribriform plate to predict the number of olfactory receptor genes that fossil mammals have. I confirmed their results and predicted gene counts in fossil whales, thereby documenting a decrease in (open full item for complete abstract)

    Committee: J. G. M. Thewissen (Advisor); Samuel Crish (Committee Member); Mary Ann Raghanti (Committee Member); Edgar Kooijman (Committee Member); Tobin Hieronymus (Committee Member) Subjects: Anatomy and Physiology; Animals; Biology; Evolution and Development; Histology; Morphology; Paleontology
  • 14. Goss, Adam An Arbitrary Lagrange-Eulerian Investigation of HRAM Shallow Jet Pre-Spurt Formation and Time Sensitivities to Impact Plate Dynamics

    Doctor of Philosophy, The Ohio State University, 2021, Aerospace Engineering

    With dry bay fires persisting as a significant contributor to aircraft vulnerability despite chronicled developments in survivability technologies, an accurate fire prediction capability remains paramount for credible vulnerability assessments. Physics based modeling of the hydrodynamic ram (HRAM) fluid deposition process is a key component of such capability, wherein capturing the first instance of fluid spurt, referred to herein as shallow jet spurts, is a core focus. Such pre-spurts as they have been formerly identified have only been witnessed sporadically in HRAM spurt experiments. ALE3D, a first-principles multi-physics code was employed to model the shallow jet spurt phenomenon with spherical projectiles impacting water-filled tanks faced with aluminum panels, such that the underlying physics and sensitivities could be explored. Development and verification of the 2Daxisymmetric model is described relative to trends observed in a prior experimental campaign. Results from the verified model suggest shallow jet spurts have at least a quadratic sensitivity to the fundamental vibrational mode of the impact plate across impact velocities 610 – 1829 m/s (2000 – 6000 ft/s). It is further explained how shallow jet spurts are arrested for impacts at the two extremes of plate rigidity. This research constitutes the first fluid-structure modeling of shallow jet spurts which future three-dimensional analyses will expound upon.

    Committee: Jeffrey Bons (Advisor) Subjects: Aerospace Engineering
  • 15. Erwin, Justin Mixed States of Infrared Light and Matter: Electromagnetic Cavities, Metal Surfaces, and Molecular Vibrations

    Doctor of Philosophy, The Ohio State University, 2021, Chemistry

    Fundamental properties of mixed states of light and matter were studied. Mixed states of surface plasmon polaritons (SPP) and the holes of mesh, treated as etalons, are called cavity mediated SPPs herein. This work presents the narrowest measured cavity mediated SPP to date which is accomplished by angle tuning square arrays of microholes in metal film, (3000 lines per inch mesh). The most important results of this work involve mixed states of etalon microcavities and condensed phase molecular vibrations, i.e. vibrational polaritons. Experiments have been conducted on materials in etalon cavities that measure mixed states and related energy splittings. These are first modeled using transfer matrix (TM) calculations that require an accurate complex and frequency dependent index of refraction. In favorable cases, they are further modeled with a cavity quantum electrodynamics (cQED) interaction Hamiltonian. The cQED method allows cavity-vibration coupling to be determined in many systems. However, this work shows the first example of changing the vibration-vibration coupling in a system, liquid acetonitrile, in which the vibrations were already Fermi coupled. Mixed states have also been studied in solvents of water, carbon tetrachloride, and benzene. There is also some preliminary work studying the decomposition reaction of hydrogen peroxide in water, as well as the molecules with CN stretches in liquids and solutions.

    Committee: James Coe (Advisor) Subjects: Chemistry; Optics; Physics
  • 16. Bradley, Rebecca Spectroscopy and Machine Learning: Development of Methods for Cancer Detection Using Mid-Infrared Wavelengths

    Doctor of Philosophy, The Ohio State University, 2021, Chemical Physics

    Cancer is a disease that affects millions of people each year, and cancer detection is currently done using costly and inefficient methods. The purpose of this research has been to develop methods that use infrared spectroscopy and machine learning to accurately and efficiently detect cancer. The vibrational information from the molecules of tissue can be accessed through infrared spectroscopy and various spectral metrics including those from spectral peak ratios, calibrant spectra, and principal component analysis of spectral libraries. This information is coupled with machine learning methods for separation and feature selection. Using these methods, two imaging experiments were conducted on SKH-1 mice with skin cancer and colorectal cancer metastatic to the liver in humans. Support vector machine learning methods were able to separate the tumor spectra from other spectra, including nontumor, with high accuracy. Support vector machines were also used to determine optimum peak ratios for separation to reduce the number of wavelengths needed. Support vector machine methods were also compared with metrics from currently used tissue staining techniques – hematoxylin and eosin – which showed that infrared spectra are more effective at separating cancer under the present conditions. These known optical techniques were also joined with infrared spectroscopy for a combined approach. Using the support vector machine decision equation, images of tissue were created to aid in the diagnosis of cancer. The methods developed were used as a basis for the design of a fast infrared probe that can detect skin cancer with high levels of accuracy in a clinical trial. The fast infrared probe was also able to separate between two different types of skin cancer – basal and squamous cell carcinomas. This prototype probe could be modified with an etalon filter to increase the efficiency of the probe when used in a clinical setting. This research develops and tests methods that show that i (open full item for complete abstract)

    Committee: James Coe Ph.D. (Advisor); Heather Allen Ph.D. (Committee Member); Sherwin Singer Ph.D. (Committee Member); Dongping Zhong Ph.D. (Committee Member) Subjects: Chemistry; Physics
  • 17. Hoehler, Jacob High Peak Power Cavity Dumped Two Micron Vertical External Cavity Surface Emitting Lasers

    Master of Science (M.S.), University of Dayton, 2020, Electro-Optics

    There exists a plethora of applications which require high-powered, pulsed laser systems within the military and scientific communities. One increasingly prevalent use is in Light Detection and Radiation (LiDAR), which currently operates mainly in the one-micron range utilizing Q-switched solid state and fiber lasers. However, a demand has risen to bring these systems into the two-micron range for its openings in the atmosphere as well as eye-safety in the target environment. Vertical External Cavity Surface Emitting Lasers (VECSELs) can help fill this gap by offering the high powered semiconductor gain in tandem with the good beam quality and flexibility offered by the external cavity. The light can then be stored in a low-loss cavity to later be extracted by dumping the cavity in multi-nanosecond long temporal pulses. In this report, the design and construction of a two-micron, cavity-dumped VECSEL will be discussed. The process from the characterization of the gain through the design and loss minimization of the cavity, through to cavity-dumping and the results will be detailed. Utilizing a 1.5 meter long cavity with an intracavity Pockels cell and thin film polarizer, peak powers of 510W in a 10ns pulse was attained. These powers were attained by gain switching the setup and minimizing the loss within the cavity to 4% per round trip. The center wavelength of the system was 2037nm. Furthermore, the spatial mode quality showed the laser to be operating single mode, with an M2 below 1.02.

    Committee: Andrew Sarangan Ph.D. (Committee Chair); Qiwen Zhan Ph.D. (Committee Member); Robert Bedford Ph.D. (Committee Member); Ricky Gibson Ph.D. (Committee Member) Subjects: Engineering; Optics
  • 18. Ridzon, Matthew Quantifying Cerebellar Movement With Fluid-Structure Interaction Simulations

    Master of Science in Engineering, University of Akron, 2020, Mechanical Engineering

    Studying human brains and spinal cords, or many other complex body parts for that matter, come with great challenges and risks when hoping to get accurate data, hopefully in real-time, in vivo, as opposed to in vitro or from a corpse. Of even more interest, are diseased members, since they possess unique traits that shine significant light into the medical community to help understand and treat countless disorders and pathologies. Having this information greatly improves the quality of life for the afflicted, but not to mention, the whole human race. Of particular interest here, is the cerebrospinal fluid flow, a water-like substance, that encases the spinal cord and pulses in and out of the brain's intracranial spaces. Upon entrance into the brain cavity from the spinal cord, it first encounters the cerebellum, the posterior lobes at the bottom of the brain. A lot of studies have been done, in vivo and in vitro, to understand its impact on the movement of the cerebellum, specifically in relation to a Chiari malformation which is characterized by herniation of the cerebellar tonsils. Pahlavian et al shows data from magnetic resonance imaging where the cerebellum of healthy patients moves approximately 100 microns. The work herein uses numerical software tools to hypothesize the cause of the cerebellum's movement. Sources vary widely about the actual material properties of the spinal cord and brain. But with the later data found from Klatt et al, estimates show material elasticity on the order of 1 kPa. With said material elasticity, numerical studies here concluded the cerebellum moves approximately 200 microns. Considering the broad variance among scientists about human tissue elasticities, fluid substance properties, geometry, etc., this was very close to Pahlavian's conclusion, thus fruitful. Two main contributors can lead to cerebellum movement, pressure and wall shear. It was determined from these numerical studies that pressure is the main contrib (open full item for complete abstract)

    Committee: Francis Loth (Advisor); Sergio Felicelli (Committee Member) Subjects: Biomechanics; Biomedical Engineering; Engineering; Fluid Dynamics; Mechanical Engineering
  • 19. Fadul, Gabrielle Comparison Study of Nanoparticle and Cyclophosphamide Deposition in Olfactory Region between Microfluidic Device and Nasal Cavity

    Master of Science, Miami University, 2019, Chemical, Paper and Biomedical Engineering

    Through inhalation foreign substances are able to travel into the nasal cavity through the olfactory region into the brain causing neurodegenerative diseases. Models such as microfluidic devices do not accurately represent this pathway. Therefore other models should be used to test the uptake of substances through the olfactory region. A nasal cavity model was created to test the olfactory pathway with gold nanoparticles and the chemotherapy drug Cyclophosphamide. The results were then compared to a microfluidic device.

    Committee: Lei Kerr (Advisor); Catherine Almquist (Committee Member); Justin Saul (Committee Member) Subjects: Biomedical Engineering; Chemical Engineering; Chemistry; Engineering; Environmental Engineering; Toxicology
  • 20. Shiyani, Dhaval Study of the Effects of Geometric Parameters and Yaw Angle on Drag Generation in Clean Rectangular Cavities

    MS, University of Cincinnati, 2018, Engineering and Applied Science: Aerospace Engineering

    In this two-part computational investigation, the effect of yaw angle (f on the drag generated by the presence of a clean sharp-edged rectangular cavity, embedded in a fully developed turbulent boundary layer, generated over a flat plate is studied, referred to hereafter as the long inlet cases; along with a study of the effect of geometric variation of fundamental cavity parameters, namely L/D & L/W ratios, for a cavity embedded in a smaller, non-fully developed turbulent boundary layer, referred to hereafter as the short inlet cases. Majority of research into cavity flows focus on the acoustic signature generated by unsteady pressure variations within the cavity, with some venturing into the search of effective acoustic suppression techniques. However, the drag caused by surface cutouts can be substantial, generating shear layer oscillations, which could alter the performance of vehicles containing said surfaces, and potentially produce damaging structural loading. This justifies the need of a study into the drag characteristics of cavities when subjected to yaw and geometric variation. Past experimental investigations suggest a flow transition within the cavity as the yaw angle is varied. Hence, to develop an improved understanding of the flow phenomena involved and the effect of the effect of f, L, D, and W variations on the drag generated within the cavities, steady state simulations were performed using OpenFOAM, an open-source CFD package [17]. For the long inlet case, a cavity with an effective L/D ratio of 16.25 and L/W ratio of 8.125 at f 900, is studied at f of 00, 300, 450, 600, 750, & 900, with an incoming freestream velocity of 25 m/s. For the short inlet cases, five L/D variations at a fixed L/W, and three L/W variations at a fixed L/D, are studied with changing f of 00, 300, 450, 600, 750, & 900 for each one of L/D and L/W variation. The steady pressure contours on the cavity faces are computed and analyzed along with computed drag coefficient. The (open full item for complete abstract)

    Committee: Peter Disimile Ph.D. (Committee Chair); Shaaban Abdallah Ph.D. (Committee Member); Milind Jog Ph.D. (Committee Member) Subjects: Engineering