Master of Science, The Ohio State University, 2022, Vision Science
Purpose: To evaluate subjective and objective refraction methods based on oriented grating targets.
Methods: Subjective and objective meridional refraction was performed on 21 young normally-sighted subjects. Both the subjective and objective refraction methods were performed with and without cycloplegia. Targets for refraction were Gaussian-attenuated square wave gratings at four orientations (0⁰, 45⁰, 90⁰, 135⁰), with a bar width equal to 2x the subject's threshold letter size (i.e. for 20/20, 10 minarc/bar width, or 3 cycles/degree). The endpoint of the refraction was the spherical lens power to achieve maximum grating contrast. Lens power at each grating orientation was determined twice, and the sphero-cylindrical correction was derived from the dioptric power for those four orientations. The objective refractive correction was based on a measurement of ocular aberrations. In both the cyclopleged and non-cyclopleged conditions, aberration coefficients were transformed from those for the measured pupil diameter to a 3.5 mm pupil. As in the subjective method, the dioptric power to maximize grating contrast was found for each orientation, and the sphero-cylindrical correction was derived from those powers. Visual acuity was measured with the result of each refraction using an adaptive, maximum-likelihood method. Visual acuities with the result of the cycloplegic refraction were measured at a second visit, at least one day after the refraction visit.
Results: Intra-session repeatability of M, J0, and J45 of dry subjective refraction was not significantly different from those found in a previous similar study (2-sample Kolmogorov-Smirnov test, p>.10). The standard deviations of M, J0, and J45 were 0.20D, 0.29D, and 0.22D, respectively, and is comparable to repeatability of standard methods of subjective refraction. Agreement between the different types of refraction was evaluated by examining differences in M, J0, J45, and in total dioptric power. Wet and (open full item for complete abstract)
Committee: Thomas Raasch (Advisor); Bradley Dougherty (Committee Member); Heather Anderson (Committee Member)
Subjects: Ophthalmology; Optics