Master of Science (MS), Ohio University, 2014, Athletic Training (Health Sciences and Professions)

Context: Current concussion guidelines call for physical and cognitive managed rest following a concussion. To better treat concussed athletes and evaluate these guidelines, objective monitoring measures are needed. The Rest and Neurocognitive Recovery Application (RNRCA) was developed for the concussed athlete and health care provider to assist in tracking concussion symptoms, daily activities, and overall wellbeing of the athlete. Objective: To validate the use of the RNRCA in monitoring physical and cognitive activity when compared to an Activity Diary. Participants: Participants who volunteered for the study were college students, intercollegiate athletes, and club sport athletes, all over the age of 18. Concussed participants were diagnosed with a concussion by a licensed athletic trainer during their regular sports season. Interventions: The study was 5 days and the AD and RNRCA were completed once every 24 hours. RNRCA logs were sent directly to the primary investigators e-mail and forwarded to the designated team athletic trainer. ADs were collected following completion of the study. Main Outcome Measures: Descriptive statistics, dependent t-tests, and intraclass correlations were run for all activities comparing the Activity Diary and RNRCA activity logs. Results: No physical, cognitive, or electronic activities showed significance when comparing the two devices that collected activity data. Behavioral activities that were most highly associated with concussion symptoms were reading, watching television, attending class, and exercising. Conclusions: RNRCA successfully collected physical and cognitive activity data in sequence to an Activity Diary. Higher power is needed in order to validate the use of the application with concussed subjects.

Committee: Cheryl Howe (Advisor) Subjects: Neurosciences; Sports Medicine

Bachelor of Arts, Wittenberg University, 2024, Exercise Science

Resistance training has become one of the most popular methods to increase muscular strength and cross-sectional area (hypertrophy). Strength is often measured by testing an individual's 1-repetition maximum (1RM) for a specific lift. Hypertrophy is measured by an increase in muscle fiber cross-sectional area of the target muscle group. Rest interval between sets is an important variable that affects both acute and chronic responses to resistance training. Prior research has found conflicting data that makes determining the most effective inter-set rest interval difficult. Most findings show that at least 3-minute rest intervals are required to see significant increases in strength and hypertrophy, but most studies also show that long rest intervals result in further increases when compared to the short rest intervals, regardless of specific times. Therefore, we hypothesized that longer inter-set rest intervals would lead to greater increases in both muscular strength and hypertrophy when compared to shorter inter-set rest intervals. This study recruited 12 participants to undergo a 4-week resistance training protocol consisting of 3 training days a week. Each training day would include the flat barbell bench press, barbell back squat, and barbell or dumbbell curls. Subjects were randomly assigned to either a 3-minute or 5-minute interest rest interval and were told to strictly follow these rest intervals. Pre- and post-tests were performed before and after the 4-week exercise protocol, consisting of heart rate, blood pressure, BIA, girth measurement, and skinfold. Between the two groups, there was no statistical difference prior to testing or post testing. When comparing within groups from prior to post testing, significant differences were found in the 3-minute group biceps skinfold, 3-minute group bench press 1RM, and 5-minute group back squat 1RM. Based on findings from this study, conclusions that can be made are that a 3-minute rest interval might be most ef (open full item for complete abstract)

Committee: John Thistlethwaite (Advisor); Matthew Collier (Committee Member); Molly Hopkins (Committee Member) Subjects: Health Sciences; Kinesiology; Sports Medicine

MARCH, University of Cincinnati, 2024, Design, Architecture, Art and Planning: Architecture

WaKeeney, Kansas, a town with fewer than 2,000 residents, sits halfway between Denver and Kansas City along a portion of I-70 that has little to see or do. The few rest stops found along the Great Plains stretch of I-70 are a series of non-places that have become increasingly dominant along our highways. These are places, often chain fast food restaurants and gas stations, have little to no relationship with their context and exist anywhere with little to no changes. The thesis is a proposal in WaKeeney, Kansas, for an alternative to the placeless conventions of the contemporary rest stop. This is not an attempt to remove non-places from society, but instead is meant to rekindle the idea behind the rest stops during the glory days of travel along roads like Route 66. At one time, every little diner and motel was unique, often due to its association to its place. As non-places continue to become more and more dominate, we lose a sense of place in structures during road travel. To draw visitors in, this project is large and intriguing. The rest stop spans nearly the entire length of the open space between the two interstate exits in WaKeeney. Since the rest stop typology is naturally geared towards travelers, it caters to the outsider's view of the state of Kansas and the Great Plains region. It is akin to a theater production, with the architecture acting as the stage. Double sided structures help create different experiences based on which side you are looking. The interior consists of a series of stage sets to create a moment that relates to its regional context, either done authentically or kitschy. The idea of place coupled with the concept of theater allows this proposal to be an experience catered towards the perception of the exciting and unique aspects of Kansas, done with kitschy and exaggerated architecture and interior design.

Committee: Vincent Sansalone M.Arch. (Committee Member); Edward Mitchell M.Arch (Committee Chair) Subjects: Architecture

M.A. (Master of Arts in English), Ohio Dominican University, 2023, English

For centuries, feminine illness has been used a way to silence and subdue women. “Feminine illness” is often referred to as hysteria, melancholia, and madness. Women have been the perceived bearers of this illness, and were considered to be the weaker sex due to ancient beliefs surrounding the physical qualities of the uterus. The first record of this illness can be traced to ancient Egyptian history in 1900 BC according to various scholars and historical documents. This thesis examines two texts: “The Female Quixote, or: The Adventures of Arabella” by Charlotte Lennox, and “The Yellow Wallpaper by Charlotte Perkins Gilman. These texts offer two differing perspectives on feminine illness in the 18th and 19th century, and mark positive changes through time surrounding this belief. Hinshaw asserts that the societal expectations the female protagonists are pressured to follow cause them to become trapped in this very society. This entrapment essentially provides the protagonists with two choices: they must either use or silence their voices in order to be free of their diagnoses. The choices they make, and the corresponding outcomes, reflect the time in which they live.

Committee: Jeremy Glazier Professor (Other); Martin Brick Dr. (Advisor) Subjects: Literature

Doctor of Philosophy, The Ohio State University, 2022, EDU Teaching and Learning

Women of color have theorized in scholarly, informal, and communal ways for centuries about the simultaneous racism, sexism, and other concurrent forms of oppression they experience (e.g., Aleman, 2018; Crenshaw, 1991; Robinson, 1851). Research demonstrates that institutional intersectional oppression has harmful effects on women of color at all levels within higher education (Gutierrez y Muhs et al., 2012; Mckee & Delgado, 2020; Niemann et al., 2020; Patton & Njoku, 2019). Such effects, coupled with alarming rates of mental health issues in graduate education (Evans et al., 2018), provide a bleak context for Black and Latine women pursuing PhDs. Using Critical Race Feminism and feminist qualitative inquiry, this dissertation illuminates how Black and Latine women PhD students within the field of education experience, resist against, and rejuvenate from gendered racism during graduate education. The central focus of this inquiry is rest, defined as a period of freedom from labor and stressors, during which one can cultivate peace of mind, body, and spirit. Drawing on data from semi-structured interviews and a collective rest space, an emerging feminist and culturally-based approach similar to an informal focus group, this study investigates a) the raced and gendered experiences of Black and Latine women PhD students in education, b) how Black and Latine women in education PhD programs conceptually and literally engage with rest while pursuing a degree, and c) how Black and Latine women in education PhD programs use rest, resistance, and rejuvenation to persist.

Committee: Timothy San Pedro (Committee Chair); Cynthia Tyson (Committee Member); Stephen Quaye (Committee Member); Michiko Hikida (Committee Member) Subjects: Black Studies; Education; Ethnic Studies; Gender Studies; Higher Education; Hispanic Americans; Womens Studies

Doctor of Philosophy, The Ohio State University, 2019, Kinesiology

Flotation-restricted environmental stimulation therapy (flotation-REST) attenuates afferent nervous system signaling and promotes relaxation of the body and mind. Despite limited research, the intervention has become increasingly popular among high-performance populations (e.g., elite athletes, military operators) seeking to accelerate recovery and enhance performance readiness. The aim of the present investigation was to determine whether a one-hour flotation-REST session could augment recovery from high-intensity resistance exercise (6 sets of 10 back squats with 2 minutes rest) known to induce significant metabolic, adrenergic and mechanical stress. Eleven healthy resistance-trained males (age: 22.5± 2.3 years; height: 176.4±6.0 cm; weight: 85.7±6.2 kg, back squat 1RM: 153.1±20.1 kg; strength to weight ratio: 1.8±0.2) completed the within-subjects cross-over controlled research study. Following flotation-REST familiarization, participants completed two exercise testing blocks separated by a two-week washout. In one testing block, the high-intensity squat protocol was immediately followed by a one-hour flotation-REST session, while recovery in the remaining block consisted of a passive control condition in a sensory-stimulating environment. Markers of metabolic stress (lactate), neuroendocrine signaling (catecholamines, cortisol, testosterone), structural damage (myoglobin, creatine kinase), inflammation (IL-6, TNF-alpha), muscular performance (squat jump, countermovement jump) and psychological perception (pain, soreness, mood, fatigue, energy) were assessed at five time points: before exercise (PRE), immediately post-exercise (IP), post 1-hour recovery (1R), twenty-four hours post-exercise (+24) and forty-eight hours post-exercise (+48). Repeated measures analysis of variance revealed muscle soreness was significantly attenuated with flotation-REST. The greatest treatment difference was observed directly following the intervention, in which the intensity (open full item for complete abstract)

Committee: William Kraemer (Advisor); Brian Focht (Committee Member); Carl Maresh (Committee Member); Jeff Volek (Committee Member) Subjects: Endocrinology; Health Sciences; Kinesiology; Sports Medicine

Doctor of Philosophy, The Ohio State University, 1979, Graduate School

Committee: Not Provided (Other) Subjects: Psychology

Doctor of Philosophy, The Ohio State University, 2013, Pharmacy

Pancreatic cancer is among the most lethal of all human diseases. With a 5-year survival of less than 6%, there is a dire need for new therapeutic options. Molecular understanding of the disease is vital to overcome barriers to effective treatment. Here we evaluate the expression of noncoding RNAs in patient tissues, cell lines, in vitro model systems and in a genetically engineered mouse model that recapitulates the disease progression in humans. Two different classes of noncoding RNAs were studied, microRNA (miRNA) and transcribed ultraconserved elements (T-UCRs). Corroborating previously published data, we identify a miRNA cluster (miR-216a, miR-216b, and miR-217) that is consistently down-regulated in the different models of the disease. These miRNAs, are pancreas enriched, and appear to be acinar cell specific. A large percentage of the 482 known T-UCRs had increased expression in pancreatic cancer tissues, cell lines and in an in vitro system that mimics the pancreatic desmoplastic reaction. We hypothesized that loss of miR-216/-217 expression might be a crucial step in regulating acinar-to-ductal metaplasia (ADM). Although historically believed to originate in the ductal cells, compounding evidence now has shifted the paradigm to an acinar cell origin of the malignancy. miR-216/-217 expression decreases using an in vitro model that mimics the ADM process. Adenovirus overexpression of miR-217 during the in vitro ADM attenuates acinar to epithelial transdifferentiation. We present evidence of indirect regulation of the epithelial cell marker CDH1 by miR-217, suggesting that miR-217 could regulate ADM though suppression of ductal markers in acinar cells. We also considered that the miRNA cluster may target master regulatory transcription factors. We demonstrate that miR-217 targets REST, a major transcriptional suppressor. We show REST protein to be up-regulated in the patient protein analyzed and that REST target genes are up-regulated in gene profiling (open full item for complete abstract)

Committee: Thomas Schmittgen (Advisor); Mamuka Kvaratskhelia (Committee Member); Kalpana Goshal (Committee Member); Mark Bloomston (Committee Member) Subjects: Molecular Biology; Oncology; Pharmaceuticals

Doctor of Philosophy (PhD), Wright State University, 2009, Computer Science and Engineering PhD

During the past seven years services centric computing has emerged as the preferred approach to architect complex software. Software is increasingly developed by integrating remotely existing components, popularly called services. This architectural paradigm, also called Service Oriented Architecture (SOA), brings with it the benefits of interoperability, agility and flexibility to software design and development. One can easily add or change new features to existing systems, either by the addition of new services or by replacing existing ones. Two popular approaches have emerged for realizing SOA. The first approach is based on the SOAP protocol for communication and the Web Service Description Language (WSDL) for service interface description. SOAP and WSDL are built over XML, thus guaranteeing minimal structural and syntactic interoperability. In addition to SOAP and WSDL, the WS-* (WS-Star) stack or SOAP stack comprises other standards and specification that enable features such as security and services integration. More recently, the RESTful approach has emerged as an alternative to the SOAP stack. This approach advocates the use of the HTTP operations of GET/PUT/POST/DELETE as standard service operations and the REpresentational State Transfer (REST) paradigm for maintaining service states. The RESTful approach leverages on the HTTP protocol and has gained a lot of traction, especially in the context of consumer Web applications such as Maps. Despite their growing adoption, the stated objectives of interoperability, agility, and flexibility have been hard to achieve using either of the two approaches. This is largely because of the various heterogeneities that exist between different service providers. These heterogeneities are present both at the data and the interaction levels. Fundamental to addressing these heterogeneities are the problems of service Description, Discovery, Data mediation and Dynamic configuration. Currently, service description (open full item for complete abstract)

Committee: Amit Sheth PhD (Committee Chair); Michael Raymer PhD (Committee Member); Lakshmish Ramaswamy PhD (Committee Member); Shu Schiller PhD (Committee Member); Guozhou Dong PhD (Committee Member); Krishnaprasad Thirunarayan PhD (Committee Member) Subjects: Computer Science

MA, University of Cincinnati, 2006, Design, Architecture, Art and Planning : Art History

American Impressionist Frederick Carl Frieseke (1874–1939) lived and worked in France for approximately forty years and achieved international success with his paintings of women in domestic interiors and gardens. In this thesis I examine three themes in Frieseke's oeuvre – women at rest, women reflected in mirrors, and the female nude – and explore how his reception in both the French and American art markets influenced his work. I decode the pictorial meanings in these images and demonstrate how they document and construct notions of womanhood around the turn of the twentieth century. This thesis contributes to the ongoing scholarly discussion of images of women in late nineteenth- and early twentieth-century art. The study also augments current scholarship on Frieseke, placing his paintings of women within a socio-historical context.

Committee: Dr. Theresa Leininger-Miller (Advisor) Subjects: Art History

Master of Science (MS), Ohio University, 1993, Civil Engineering (Engineering)

As an alternative energy source, solar energy can be used to produce hot water and electricity in public rest areas. To investigate performance and economics of such applications, two solar systems were instrumented at high way rest areas in Lake and Butler county in I-90 and I-75 respectively. From the data collected, average annual solar contributions were calculated as 52% for Lake county and 72% for Butler county. Both solar systems were modeled using TRNSYS subroutines and validated results. This program could be used in designing solar domestic hot water systems for other highway rest facilities.

Committee: Glenn Hazen (Advisor) Subjects: Engineering, Civil

Master of Science (MS), Ohio University, 1992, Civil Engineering (Engineering)

Solar power as partial source of energy for public highway rest areas is being evaluated in Ohio. In this study two highway rest areas were instrumented with solar water heating system and monitoring equipment. Results for one of the two instrumented rest areas were monitored over a one year period. The performance of the solar collector and their components were evaluated and economical comparisons made between the conventional system and the solar system using life-cycle cost analysis. In comparison to the conventional system, the solar hot water system was found to be an economical alternative energy source. The results suggest that solar contribution was only 4% in winter but 100% in summer. The emergency lighting provided by a photovoltaic system was enthasiaitically endorsed by rest area personnell. Power usage indicates that the system was over designed.

Committee: Glenn Hazen (Advisor) Subjects: Engineering, Civil

MARCH, University of Cincinnati, 2013, Design, Architecture, Art and Planning: Architecture

Within the United States, buildings and structures constructed less than 100 years ago have deteriorated, eliminating artifacts that enable current generations to investigate and understand the culture from previous time periods. The American fascination with cars cultivated an accelerated quest for speed in getting from one place to another, ultimately causing buildings to be built that were not made to last. Relatively few structures remain, but rather personal stories that survive until today to explain the rise, boom, and fall of Route 66. This roadway serves as an American cultural icon, only in use for several decades, but today falling into ruin. And as we speed along highways and freeways, we become numb to our surroundings, only stopping for shocking or awe-inspiring images. As our society becomes increasingly dependent upon technology and travelling quickly from place to place, it is rare that we take the time to recognize and comprehend space and place while in motion. This thesis examines the construction of a historical narrative within the context of a mobile environment along Route 66. Using the broader context of Missouri as a site, it analyzes the role that movement has on architectural perception through a series of eleven rest stops using the techniques of rhythm, repetition, sequentiality, and montage in order to communicate a history through the juxtapositions of people in place.

Committee: Michael McInturf M.Arch (Committee Chair); Aarati Kanekar Ph.D. (Committee Member) Subjects: Architecture