PHD, Kent State University, 2019, College of Arts and Sciences / School of Biomedical Sciences
The overall goal of this work is to relate stress and emotional state to the processes of hearing and communication. We focus on two forms of the aforementioned relationship, investigating 1. Situations in which there is a particularly salient relationship among stress, emotional state, and hearing or acoustic communication and 2. How these relationships differ between males and females. Experiments in Aim 1 focus on the behavioral and hormonal responses of typical male and female mice to vocal communication signals, in order to understand the communicative function of four social vocalization categories. Aim 2 investigates the relationship between emotional state and tinnitus, the perception of sound in the absence of an external stimulus (Jastreboff, 1995), in males and females, utilizing behavioral and hormonal assays. Together, the Aims identify behavioral and hormonal components of the relationship between stress and emotional state and the processes of hearing and communication, as they differ between males and females. This work utilizes CBA/CaJ mice, a strain of mice that is widely used as a model of mammalian hearing and communication (Portfors 2007; Radziwon et al., 2009; Ohlemiller et al., 2010; Longenecker & Galazyuk, 2011; Grimsley et al., 2016).
Committee: Jeffrey Wenstrup (Advisor); Alexander Galazyuk (Committee Member); Sheila Fleming (Committee Member); Bruna Mussoi (Committee Member); Joel Hughes (Committee Member)
Subjects: Neurosciences; Psychology