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A Comparison of Pupillary Responses from Two Pupillometers and their Associations with Axial Length and Refractive Error

Dawson, Dustin
http://rave.ohiolink.edu/etdc/view?acc_num=osu1712444125414731

Abstract Details

2024, Master of Science, Ohio State University, Vision Science.
Globally, the number of people with myopia is high and is expected to impact roughly 50% of the population by 2050. Myopia has many pathological complications associated with ocular health and consequences can, in rare instances, lead to blindness. Evidence-based studies regarding the development of myopic refractive error have sought to determine mechanisms for its onset and progression, however the exact mechanism(s) has not been identified. It is suggested that a complex interplay of genetic and environmental factors lead to myopic refractive error. One particular mechanism is intra-retinal dopamine release associated with light-stimulated intrinsically photosensitive retinal ganglion cells (ipRGCs) that are most sensitive to blue light (480nm). The purpose of this study is to compare the older RAPDx pupillometer to the newer EyeKinetix pupillometer to determine if the brighter stimuli used by EyeKinetix pupillometry is able to generate an association between refractive error and axial length. By utilizing alternating and single-color stimuli, it is hypothesized that pupil constrictions will be more robust with the brighter stimuli and that myopic subjects will have less adaptive pupillary constrictions throughout the course of the procedure than those who are less myopic/hyperopic.
Donald Mutti (Advisor)
Jeffrey Walline (Committee Member)
Andrew Hartwick (Committee Member)
61 p.
Ophthalmology
Pupillometry. Refractive error. Associations. Comparison.

Recommended Citations

Citations

  • Dawson, D. (2024). A Comparison of Pupillary Responses from Two Pupillometers and their Associations with Axial Length and Refractive Error [Master's thesis, Ohio State University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=osu1712444125414731

    APA Style (7th edition)

  • Dawson, Dustin. A Comparison of Pupillary Responses from Two Pupillometers and their Associations with Axial Length and Refractive Error. 2024. Ohio State University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=osu1712444125414731.

    MLA Style (8th edition)

  • Dawson, Dustin. "A Comparison of Pupillary Responses from Two Pupillometers and their Associations with Axial Length and Refractive Error." Master's thesis, Ohio State University, 2024. http://rave.ohiolink.edu/etdc/view?acc_num=osu1712444125414731

    Chicago Manual of Style (17th edition)

osu1712444125414731
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© 2024, some rights reserved.Creative Commons License A Comparison of Pupillary Responses from Two Pupillometers and their Associations with Axial Length and Refractive Error by Dustin Dawson is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License. Based on a work at etd.ohiolink.edu.
This open access ETD is published by The Ohio State University and OhioLINK.
Release 3.2.12