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Multi-Frequency and Multi-Sensor Impedance Sensing Platform for Biosensing Applications

Bhatnagar, Purva
http://orcid.org/0000-0001-6118-7276
http://rave.ohiolink.edu/etdc/view?acc_num=ucin1543999395772179

Abstract Details

2018, PhD, University of Cincinnati, Engineering and Applied Science: Electrical Engineering.
The future of disease diagnostics and health care wearables lies in the development of low-cost sensors and devices that can detect minute traces of pathogens or antigens from body fluids. These devices will allow patients to run point of care diagnostics tests, thereby saving time and cost of running clinical tests and ultimately can provide early stage disease diagnosis and enable physicians to provide better-personalized treatment. There have been developments that focus on integrating multiple different tests into a single device that measures analytes from biofluids. Detection of glucose together with some single ions in a single device and test is the current attractive research advancement. Electrochemistry Impedance Spectroscopy (EIS) is widely popular in the medical field where it is used to analyze biological materials as well as characterization of body fluids. It is a complex technique requiring expensive equipment that is also bulky making it difficult to integrate into small form-factor systems that are handheld, wearable and intended for use in point of care testing. This research work focused on developing a proof of concept prototype system with a flexible architecture that can be used for testing multiple sensors using EIS electroanalytical technique. The system is based on an embedded system design to be factored to achieve small valuation time for results along with being compact and portable enough to be used outside laboratory bench setting. The prototype successfully calculates the magnitude and phase of the impedance responses multiple electrochemical cells. The device transmits test data wirelessly to a personal computer or tablet which works together with an analysis and control display.
Fred Beyette, Ph.D. (Committee Chair)
Jason Heikenfeld, Ph.D. (Committee Member)
Carla Purdy, Ph.D. (Committee Member)
Ryan White, Ph.D. (Committee Member)
Philip Wilsey, Ph.D. (Committee Member)
118 p.
Electrical Engineering
Multi-sensor Impedance Sensing; Electrochemical Impedance Spectroscopy; Health Monitoring Systems; Biosensing Applications; Analog Front End; Portable Potentiostat

Recommended Citations

Citations

  • Bhatnagar, P. (2018). Multi-Frequency and Multi-Sensor Impedance Sensing Platform for Biosensing Applications [Doctoral dissertation, University of Cincinnati]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1543999395772179

    APA Style (7th edition)

  • Bhatnagar, Purva. Multi-Frequency and Multi-Sensor Impedance Sensing Platform for Biosensing Applications. 2018. University of Cincinnati, Doctoral dissertation. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=ucin1543999395772179.

    MLA Style (8th edition)

  • Bhatnagar, Purva. "Multi-Frequency and Multi-Sensor Impedance Sensing Platform for Biosensing Applications." Doctoral dissertation, University of Cincinnati, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1543999395772179

    Chicago Manual of Style (17th edition)

ucin1543999395772179
204
© 2018, all rights reserved.
This open access ETD is published by University of Cincinnati and OhioLINK.