Skip to Main Content
 

Global Search Box

 
 
 

ETD Abstract Container

Abstract Header

Lobster (Panulirus interruptus) Striated Muscle Sarcomeres Expand Non-Uniformly During Passive Lengthening

Fender, John Matthew
http://orcid.org/0000-0002-4950-4723
http://rave.ohiolink.edu/etdc/view?acc_num=ouashonors1651619623069186

Abstract Details

2022, Bachelor of Sciences, Ohio University, Biological Sciences.
When a muscle is passively stretched, the sarcomeres within its fibers necessarily lengthen. Historically, the sarcomeres have been thought to lengthen uniformly as the muscle lengthens. However, preliminary unpublished work in the Hooper lab has suggested that, during the period of passive force decline following muscle stretch (see Introduction), muscles have non-uniform sarcomere lengths, and unpublished models show that decay of this non-uniformity can replicate the decline in passive force that occurs following muscle stretch. To fully investigate these preliminary observations, I used anti-myosin and phalloidin antibodies to view the thin and thick filaments of lobster (Panulirus interruptus) stomatogastric pyloric muscles fixed at different times after rapid stretches. Muscles fixed immediately after stretch contained sarcomeres lengthened to a variety of lengths and others at the unstretched length. Lobster stomatogastric sarcomeres therefore do not lengthen uniformly immediately after stretch. Sarcomeres of muscles fixed 5 seconds after stretch still showed a variety of sarcomere lengths, but with fewer unstretched sarcomeres and more areas where the sarcomeres had lengthened to a uniform length. Almost all sarcomeres of muscles fixed 10 seconds after stretch had the same length. This decrease in the sarcomere length range over time shows that, as passive force declined, the rates and amplitudes of sarcomere lengthening decreased, resulting in the sarcomeres achieving a uniform length as muscle passive force approached its steady-state value. These data suggest that the probability of any single sarcomere lengthening, and the amount it lengthens if it does so, is a function of the force acting on the sarcomere at each time following stretch. In summary, these data show that lobster pyloric muscle sarcomeres expand at non-uniform rates, and to non-uniform lengths, as a function of the passive force they experience following muscle stretch.
Scott Hooper (Advisor)
39 p.
Anatomy and Physiology; Animal Sciences; Animals; Biology; Biomechanics
sarcomere expansion; passive force; passive stretch; non-uniform expansion; pyloric muscles; connectin

Recommended Citations

Citations

  • Fender, J. M. (2022). Lobster (Panulirus interruptus) Striated Muscle Sarcomeres Expand Non-Uniformly During Passive Lengthening [Undergraduate thesis, Ohio University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=ouashonors1651619623069186

    APA Style (7th edition)

  • Fender, John. Lobster (Panulirus interruptus) Striated Muscle Sarcomeres Expand Non-Uniformly During Passive Lengthening . 2022. Ohio University, Undergraduate thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=ouashonors1651619623069186.

    MLA Style (8th edition)

  • Fender, John. "Lobster (Panulirus interruptus) Striated Muscle Sarcomeres Expand Non-Uniformly During Passive Lengthening ." Undergraduate thesis, Ohio University, 2022. http://rave.ohiolink.edu/etdc/view?acc_num=ouashonors1651619623069186

    Chicago Manual of Style (17th edition)

ouashonors1651619623069186
151
© 2022, all rights reserved.
This open access ETD is published by Ohio University Art and Sciences Honors Theses and OhioLINK.