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Bibber_Dissertation_Final_7.20.22.pdf (789.29 KB)

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The Association Between Molar Incisor Hypomineralization and Early Environmental Exposures

Bibber, Erin
http://orcid.org/0000-0003-1313-1440
http://rave.ohiolink.edu/etdc/view?acc_num=osu1657197061332578

Abstract Details

2022, Master of Science, Ohio State University, Dentistry.
Purpose: To determine an etiological association between the presence and severity of Molar Incisor Hypomineralization (MIH) and environmental exposures (pre-, peri-, or postnatal), early childhood illness, antibiotic use, systemic disease, race/ethnicity, or socioeconomic status. Methods: This was a hospital-based, nested case-control study of children 6-17 years old identified as having MIH via clinical exam. MIH severity was rated using the European Academy of Pediatric Dentistry (EAPD) scale. A retrospective chart review of subjects identified as having MIH, along with their age-matched controls without a diagnosis of MIH, examined the potential relationships between environmental and social factors and MIH diagnosis. Results: The study cohort was analyzed using logistic regression for associations between demographic variables and MIH. MIH was not significantly associated with age, race, language, ethnicity, or insurance type. Patients who had the DTaP Vaccine were less likely to have MIH (Odds ratio = 0.3, P-value = 0.01) and severe MIH (Odds Ratio=0.2, P-value=0.0003) than patients who did not have DTAP vaccine. Statistical analysis showed near significant associations between histories of otitis media, passive smoke exposure, and asthma for patients with an increased incidence for mild MIH. Conclusions: Molar Incisor Hypomineralization remains a multidimensional, multi-factorial diagnosis with several potential etiological associations. The DTaP vaccination status may be a variable of interest for future MIH studies. Prospective studies with increased sample size and consistent medical record information are needed to further evaluate etiological associations.
Daniel Claman (Advisor)
Ashok Kumar (Committee Member)
Kimberly Hammersmith (Committee Member)
Janice Townsend (Committee Member)
Paul Casamassimo (Committee Member)
28 p.
Dental Care; Dentistry

Recommended Citations

Citations

  • Bibber, E. (2022). The Association Between Molar Incisor Hypomineralization and Early Environmental Exposures [Master's thesis, Ohio State University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=osu1657197061332578

    APA Style (7th edition)

  • Bibber, Erin. The Association Between Molar Incisor Hypomineralization and Early Environmental Exposures. 2022. Ohio State University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=osu1657197061332578.

    MLA Style (8th edition)

  • Bibber, Erin. "The Association Between Molar Incisor Hypomineralization and Early Environmental Exposures." Master's thesis, Ohio State University, 2022. http://rave.ohiolink.edu/etdc/view?acc_num=osu1657197061332578

    Chicago Manual of Style (17th edition)

osu1657197061332578
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This open access ETD is published by The Ohio State University and OhioLINK.