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Westbrook MA Thesis Final.pdf (1.37 MB)

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The Relation of Illness Perception to Psychological Distress and Physical Symptom Burden in Relapsed/Refractory Chronic Lymphocytic Leukemia

Westbrook, Travis Dexter
http://rave.ohiolink.edu/etdc/view?acc_num=osu1416781156

Abstract Details

2014, Master of Arts, Ohio State University, Psychology.
Chronic lymphocytic leukemia (CLL) is the most prevalent adult leukemia and has no known cure. The course of CLL is atypical, often beginning with indolent disease that may or may not require immediate treatment, followed by repeated cycles of aggressive therapy, stable disease, and relapse. Despite these factors, knowledge of psychological functioning of these patients is limited. The current study examined the relation of illness perception to psychological distress and physical symptom burden in a sample of relapsed/refractory CLL patients (N=147) receiving Ibrutinib. Participants completed measures of illness perception (BIPQ), psychological distress (BDI-II, IES-R, SF-12 MCS) and physical symptom burden (SF-12 PCS, FSI, BPI) at baseline and two-months later. Regression analyses revealed that above and beyond disease relevant variables such as treatment history, age, and comorbidities, baseline illness perception was related to all measures of psychological distress and physical symptom burden at baseline (ps < .05), and all measures except for pain at follow-up (ps < .05). Follow-up analyses indicated that the individual illness perception components of consequences, emotional representation, identity, and illness concern might be particularly relevant to psychological and physical functioning of patients with CLL. Results highlight the critical role of subjective illness perception in the experience of distress and burden from physical symptoms, even among patients with cyclical and relapsing disease. Clinical implications and future directions to develop this line of research are discussed.
Barbara Andersen (Advisor)
Steven Beck (Committee Member)
Charles Emery (Committee Member)
105 p.
Psychology
chronic lymphocytic leukemia; illness perception; distress; symptom burden

Recommended Citations

Citations

  • Westbrook, T. D. (2014). The Relation of Illness Perception to Psychological Distress and Physical Symptom Burden in Relapsed/Refractory Chronic Lymphocytic Leukemia [Master's thesis, Ohio State University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=osu1416781156

    APA Style (7th edition)

  • Westbrook, Travis. The Relation of Illness Perception to Psychological Distress and Physical Symptom Burden in Relapsed/Refractory Chronic Lymphocytic Leukemia. 2014. Ohio State University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=osu1416781156.

    MLA Style (8th edition)

  • Westbrook, Travis. "The Relation of Illness Perception to Psychological Distress and Physical Symptom Burden in Relapsed/Refractory Chronic Lymphocytic Leukemia." Master's thesis, Ohio State University, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=osu1416781156

    Chicago Manual of Style (17th edition)

osu1416781156
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This open access ETD is published by The Ohio State University and OhioLINK.