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Gabrielle Fadul Thesis 12_4_19.pdf (2.06 MB)

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Comparison Study of Nanoparticle and Cyclophosphamide Deposition in Olfactory Region between Microfluidic Device and Nasal Cavity

Fadul, Gabrielle Nicole
http://rave.ohiolink.edu/etdc/view?acc_num=miami1575465625992011

Abstract Details

2019, Master of Science, Miami University, Chemical, Paper and Biomedical Engineering.
Through inhalation foreign substances are able to travel into the nasal cavity through the olfactory region into the brain causing neurodegenerative diseases. Models such as microfluidic devices do not accurately represent this pathway. Therefore other models should be used to test the uptake of substances through the olfactory region. A nasal cavity model was created to test the olfactory pathway with gold nanoparticles and the chemotherapy drug Cyclophosphamide. The results were then compared to a microfluidic device.
Lei Kerr (Advisor)
Catherine Almquist (Committee Member)
Justin Saul (Committee Member)
47 p.
Biomedical Engineering; Chemical Engineering; Chemistry; Engineering; Environmental Engineering; Toxicology
microfluidic device, nasal cavity model, cyclophosphamide, nanoparticles, drug delivery, olfactory region

Recommended Citations

Citations

  • Fadul, G. N. (2019). Comparison Study of Nanoparticle and Cyclophosphamide Deposition in Olfactory Region between Microfluidic Device and Nasal Cavity [Master's thesis, Miami University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=miami1575465625992011

    APA Style (7th edition)

  • Fadul, Gabrielle. Comparison Study of Nanoparticle and Cyclophosphamide Deposition in Olfactory Region between Microfluidic Device and Nasal Cavity. 2019. Miami University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=miami1575465625992011.

    MLA Style (8th edition)

  • Fadul, Gabrielle. "Comparison Study of Nanoparticle and Cyclophosphamide Deposition in Olfactory Region between Microfluidic Device and Nasal Cavity." Master's thesis, Miami University, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=miami1575465625992011

    Chicago Manual of Style (17th edition)

miami1575465625992011
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© 2019, some rights reserved.Creative Commons License Comparison Study of Nanoparticle and Cyclophosphamide Deposition in Olfactory Region between Microfluidic Device and Nasal Cavity by Gabrielle Nicole Fadul is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License. Based on a work at etd.ohiolink.edu.
This open access ETD is published by Miami University and OhioLINK.