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EJ Thesis 2020.pdf (11.17 MB)

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DOES EARLY MANIPULATION OF OXYTOCIN INFLUENCE SEROTONIN INNERVATION WITHIN THE HIPPOCAMPUS?

Janosik, Emma
http://rave.ohiolink.edu/etdc/view?acc_num=kent1595767756096777

Abstract Details

2020, MA, Kent State University, College of Arts and Sciences / Department of Anthropology.
In order for any type of social relationship to form, social recognition and social memory must be maintained as they provide the foundation on which social relationships are built. Oxytocin (OT) has been correlated to a variety of other prosocial behaviors such as pair bonding, social recognition memory, and trust in a wide variety of species. Serotonin plays a role in regulating OT levels and expression, acting on OT by way of 5HT receptors that are located in the PVN and SON. Together, OT and serotonin work in concert to affect social behavior in primates and rodents, which relies on intact social recognition ability. The hippocampus plays a vital role in social recognition and OT and 5HT act within this region to influence memory and social behaviors. Previous research discovered that OT manipulation to male prairie voles on the first day of life altered serotonin expression in adult brain regions involved in social behaviors, especially aggression. The current project will build on these findings by evaluating whether early exposure to OT or its antagonist alters serotonin within the hippocampus of prairie voles. We expect that there will be differences in the amount of serotonin based on the treatment of either high OT, low OT, OTA, or the saline control in regions of the hippocampus. However, our results indicated that OT manipulation does not have an effect on serotonin expression in the adult hippocampus.
Mary Ann Raghanti (Advisor)
Linda Spurlock (Committee Member)
Richard Meindl (Committee Member)
40 p.
Biology; Physical Anthropology
OT, serotonin, hippocampus, prairie vole

Recommended Citations

Citations

  • Janosik, E. (2020). DOES EARLY MANIPULATION OF OXYTOCIN INFLUENCE SEROTONIN INNERVATION WITHIN THE HIPPOCAMPUS? [Master's thesis, Kent State University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=kent1595767756096777

    APA Style (7th edition)

  • Janosik, Emma. DOES EARLY MANIPULATION OF OXYTOCIN INFLUENCE SEROTONIN INNERVATION WITHIN THE HIPPOCAMPUS? 2020. Kent State University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=kent1595767756096777.

    MLA Style (8th edition)

  • Janosik, Emma. "DOES EARLY MANIPULATION OF OXYTOCIN INFLUENCE SEROTONIN INNERVATION WITHIN THE HIPPOCAMPUS?" Master's thesis, Kent State University, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=kent1595767756096777

    Chicago Manual of Style (17th edition)

kent1595767756096777
310
© 2020, all rights reserved.
This open access ETD is published by Kent State University and OhioLINK.