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Optical Steering of Microbubbles for Nanoparticle Transport

Krishnappa, Arjun
http://rave.ohiolink.edu/etdc/view?acc_num=dayton1469461239

Abstract Details

2016, Master of Science (M.S.), University of Dayton, Electrical Engineering.
Microbubbles are increasingly playing an important role in medicine and environmental waste management. In medicine, microbubbles coated with nanoparticles are being used for directed drug and gene delivery. In water treatment, microbubbles can trap nano-sized contaminants which can then be removed. Microbubbles can be used to remove unwanted nanoparticles from the bloodstream. Precise manipulation of microbubbles with and without nanoparticles is essential to achieve effective drug and gene delivery and waste cleanup. With these applications in mind, in this research, optical manipulation of microbubbles, and microbubbles coated with metallic nanoparticles, is investigated, both theoretically and experimentally. First, an equivalent force model on a microbubble by a focused optical beam is developed, starting from the force on a single induced dipole. This is extended to the case of microbubbles coated with metallic nanoparticles. Theoretical predictions are compared with experimental results. A focused laser beam, introduced in the vicinity of microbubbles of different sizes, attracts the microbubbles. The average velocities of these microbubbles can be related to the force imparted by the laser beam. Laser steering of the microbubbles is also experimentally demonstrated. It is shown that nanoparticles have a negligible effect on the manipulation of nanoparticle-surrounded microbubbles.
Partha Banerjee (Advisor)
Joseph Haus (Committee Member)
John Loomis (Committee Member)
Donald Kessler (Committee Member)
58 p.
Electromagnetics; Nanotechnology
Nanoparticle, Microbubble, Nanoparticle-surrounded Microbubble, Gaussian Beam, Transport

Recommended Citations

Citations

  • Krishnappa, A. (2016). Optical Steering of Microbubbles for Nanoparticle Transport [Master's thesis, University of Dayton]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=dayton1469461239

    APA Style (7th edition)

  • Krishnappa, Arjun. Optical Steering of Microbubbles for Nanoparticle Transport. 2016. University of Dayton, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=dayton1469461239.

    MLA Style (8th edition)

  • Krishnappa, Arjun. "Optical Steering of Microbubbles for Nanoparticle Transport." Master's thesis, University of Dayton, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=dayton1469461239

    Chicago Manual of Style (17th edition)

dayton1469461239
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© 2016, all rights reserved.
This open access ETD is published by University of Dayton and OhioLINK.