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Full text release has been delayed at the author's request until August 16, 2026

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LATE-GADOLINIUM ENHANCEMENT PREDICTS APPROPRIATE DEVICE THERAPIES IN NON-ISCHEMIC RECIPIENTS OF PRIMARY PREVENTION IMPLANTABLE CARDIOVERTER-DEFIBRILLATORS

Abstract Details

2024, Master of Sciences, Case Western Reserve University, Clinical Research.
In 344 patients with non-ischemic cardiomyopathy with a prophylactic implantable cardioverter-defibrillator who underwent cardiac magnetic resonance imaging within 12 months prior to device implantation, significant burden of late-gadolinium enhancement was a strong predictor of appropriate device therapies (hazard ratio 2.99, 95% CI 1.48- 6.02, p=0.002) but not of all-cause mortality, heart transplant, or left ventricular assist device implantation (hazard ratio 1.34, 95% CI 0.78-2.29, p=0.287). This suggests LGE burden is a relatively specific predictor of sudden cardiac arrest risk and therefore could potentially be used during evaluation for prophylactic ICD implantation.
Jakub Sroubek, MD, PhD (Committee Chair)
Venugopal Menon, MD (Committee Member)
James Spilsbury, PhD, MPH (Committee Member)
42 p.

Recommended Citations

Citations

  • Kiang, A. (2024). LATE-GADOLINIUM ENHANCEMENT PREDICTS APPROPRIATE DEVICE THERAPIES IN NON-ISCHEMIC RECIPIENTS OF PRIMARY PREVENTION IMPLANTABLE CARDIOVERTER-DEFIBRILLATORS [Master's thesis, Case Western Reserve University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=case1721260171794304

    APA Style (7th edition)

  • Kiang, Alan. LATE-GADOLINIUM ENHANCEMENT PREDICTS APPROPRIATE DEVICE THERAPIES IN NON-ISCHEMIC RECIPIENTS OF PRIMARY PREVENTION IMPLANTABLE CARDIOVERTER-DEFIBRILLATORS. 2024. Case Western Reserve University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=case1721260171794304.

    MLA Style (8th edition)

  • Kiang, Alan. "LATE-GADOLINIUM ENHANCEMENT PREDICTS APPROPRIATE DEVICE THERAPIES IN NON-ISCHEMIC RECIPIENTS OF PRIMARY PREVENTION IMPLANTABLE CARDIOVERTER-DEFIBRILLATORS." Master's thesis, Case Western Reserve University, 2024. http://rave.ohiolink.edu/etdc/view?acc_num=case1721260171794304

    Chicago Manual of Style (17th edition)