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Degree

MS, University of Cincinnati, Medicine : Epidemiology (Environmental Health), 2008.

Abstract

Relation between Dietary Manganese Intake and Biological Markers of Manganese ExposureAbstract Manganese is an essential trace element, yet can be toxic in excess. The inter- and intra- individual variations in manganese levels in different biological media make research difficult. This study examined the relationship between dietary Mn intake and blood Mn. Methods: Subjects were recruited through the Cincinnati Lead study cohort. The Youth/Adolescent Questionnaire was used to evaluate the dietary intake of manganese. Results: The mean manganese dietary intake was 3.25 mg±2.06 (SD). The mean blood manganese concentration was 0.8mg/dl±0.36 (SD). The Spearman rank correlation coefficient between dietary manganese intake and blood manganese was not significant (P value= 0.99). Conclusions: We found no correlation between dietary manganese intake and blood manganese. This is due to our small sample size and the use of the YAQ that has not been designed specifically to measure manganese. More studies are needed to better understand the effect of dietary manganese intake on blood manganese.

Subject Headings

Epidemiology

Keywords

Dietary Manganese; Blood Manganese; Youth/Adolescent Questionnaire

Committee / Advisors

Erin Haynes, Dr.P.H (Committee Chair)
Paul Succop, Ph.D (Committee Member)
Tianying Wu, M.D,Ph.D,Sc.M (Committee Member)

Pages

39p.

Document number: ucin1211985289
Permalink: http://rave.ohiolink.edu/etdc/view?acc_num=ucin1211985289

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