Display Full Text | Download Full Text
1.06 MB PDF file

Degree

Doctor of Philosophy, University of Akron, Chemistry, 2005.

Abstract

This dissertation discusses the synthesis of different N-heterocyclic carbene precursors, the synthesis of an N-heterocyclic carbene from the precursor, the synthesis of N-heterocyclic carbene complexes of platinum and rhodium, as well as the transfer of N-heterocyclic carbenes from silver to rhodium, and to a smaller extent about the synthesis of previous heterocyclynes. In Chapter 1, the properties and preparation of N-heterocyclic carbenes and carbene salts are discussed. The bonding of N-heterocyclic carbenes as opposed to the bonding of Fischer and Schrock carbenes to metal centers is reviewed. The synthesis of platinum complexes of N-heterocyclic carbenes is illustrated. The synthesis of some of the many heterocyclynes with platinum at the corners is also discussed. The synthesis of the first silver N-heterocyclic carbene complex to use silver(I) oxide is discussed as well as the transfer of the carbene from silver to other metals with an emphasis on the transfer to rhodium. The synthesis of the various rhodium complexes of N-heterocyclic carbenes is also discussed. In Chapter 2 the synthesis of the first bis(N-heterocyclic carbene) complex of platinum is discussed as well as the synthesis of the building blocks to form the heterocyclyne. The high yield synthesis of the heterocyclyne composed of N-heterocyclic carbene platinum complexes at the corners and butadiyde fragments on the periphery is illustrated. In Chapter 3 the syntheses of the N-heterocyclic carbene complexes of silver are reported as well as the first transfer of a carbene from silver to rhodium trichloride hydrate, a necessary step in the direction of using N-heterocyclic carbene complexes of rhodium as radiopharmceuticals. An alternate approach to the synthesis of a rhodium N-heterocyclic carbene complex is also discussed.

Subject Headings

Chemistry, Inorganic

Keywords

N-heterocyclic carbene; heterocyclyne; platinum; copper coupling

Advisor

Wiley J. Youngs

Document number: akron1116249871
Permalink: http://rave.ohiolink.edu/etdc/view?acc_num=akron1116249871

This ETD has been downloaded 701 times (through March 2013)